Structural mechanism for guanylate-binding proteins (GBPs) targeting by the Shigella E3 ligase IpaH9.8
Fig 7
Structure of farnesylated GBP1.
(a) An enlarged image of the farnesyl binding pocket. (b) GBP1F (green) is superimposed onto apo GBP1 (blue, PDB ID: 1DG3). The farnesyl group (Far) is shown as magenta spheres. Rotation of the C-terminal region in GBP1F is indicated by a curved arrow.